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Breaking down cancer with genomics

Donor funding has played a pivotal role in advancing genomics research
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Genomics allows individualize treatments for cancer patients, explains Dr. Howard Lim, medical oncologist, BC Cancer.

B次元官网网址淚t was like a miracle.B次元官网网址

Trish Keating was diagnosed with colon cancer in 2010 and after surgery, chemotherapy and radiation treatment, she was told in 2013 when her cancer returned that it was terminal.

After enrolling in the Personalized Onco-Genomics (POG) Program at BC Cancer, the team of experts discovered TrishB次元官网网址檚 cancer was driven by a specific protein. They then identified and administered an existing blood pressure medication that is known to block pathways to that protein.

The results were rapid and dramatic: eight weeks after starting her new treatment, Trish was tumour-free.

B次元官网网址淚tB次元官网网址檚 still so hard to believe,B次元官网网址 says Trish. B次元官网网址淚 was months away from death.B次元官网网址

TrishB次元官网网址檚 experience is just one example of how genomics B次元官网网址 where experts deploy whole genome analysis to inform individual treatment planning for patients B次元官网网址 is transforming cancer care for people across B.C.

B次元官网网址淭he use of genomics is trying to understand the blueprint B次元官网网址 what we call the genome B次元官网网址 to a cancer, and by understanding that blueprint we can then start to individualize treatments for patients,B次元官网网址 says Dr. Howard Lim, medical oncologist, BC Cancer. B次元官网网址淕enomics will change not only how we treat cancer, but also how we detect and prevent cancer.B次元官网网址

Cancer genomes are as unique as a fingerprint, and no two genomes are identical. Therefore, says Dr. Lim, cancer treatment can no longer be one-size-fits-all.

B次元官网网址淲eB次元官网网址檙e beginning to understand that not all cancers are the same and certain ones respond differently to different treatments, or donB次元官网网址檛 respond at all to particular treatments,B次元官网网址 he says. B次元官网网址淲ith this knowledge we can begin to tailor the type of chemotherapy or targeted agents that we can use for treating specific cancers.B次元官网网址

Dr. Lim says donor funding has played a pivotal role in advancing genomics research, which is also the fundraising focus of BC Cancer FoundationB次元官网网址檚 Inspiration Gala on Nov. 2.

B次元官网网址淭he basic science we do to help further all of this research is thanks to donor support B次元官网网址 it makes a huge impact to all of us in the clinic,B次元官网网址 says Dr. Lim. B次元官网网址淚n fact, a lot of the research and treatments weB次元官网网址檝e moved forward with is because of BC Cancer Foundation donors.B次元官网网址

You can help transform the standard of cancer care with genomically informed treatments for British Columbians facing cancer. Learn more at .



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