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Company planning to make COVID-19 vaccine in Canada could go out of business

US-based Novavax told investors changing market is creating significant uncertainty
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Scientists examine a step in the vaccine purification process as they design updates to the NovavaxB次元官网网址檚 COVID-19 shots in the companyB次元官网网址檚 research laboratory on May 24, 2022, in Gaithersburg, Md. THE CANADIAN PRESS/AP-Angie Wang

An American company that signed a deal with the federal government to produce COVID-19 vaccines in Montreal has warned investors it could go out of business within the year.

Executives at Maryland-based Novavax told investors on a conference call Tuesday that there is significant uncertainty surrounding the companyB次元官网网址檚 ability to continue funding operations as the market for COVID-19 vaccines changes.

B次元官网网址淲hile our current business plan and cash flow forecast estimate that we have sufficient capital available to fund our operations for the next 12 months, we recognize that this plan is subject to significant uncertainty,B次元官网网址 Jim Kelly, NovavaxB次元官网网址檚 chief financial officer, said on the call.

He said the company, which lost more than $600 million last year, doesnB次元官网网址檛 expect to sell any new vaccine during the first three months of 2023 and there are fears that funding from the United States government could be cut.

The company, which has more than $1.3 billion in cash in hand, is counting on its ability to develop and sell an updated COVID-19 vaccine next fall and is cutting costs, Kelly told investors.

In February 2021, the federal government announced a deal with Novavax to begin producing its vaccine at a National Research Council facility in Montreal.

At the time, Industry Minister Fran莽ois-Philippe Champagne said the facility B次元官网网址 which has the potential to produce around two million doses of vaccine a month B次元官网网址 would be in position to begin production at the end of 2021.

However, on an NRC website last updated in December, the federal science and technology agency said it is still working on the B次元官网网址渢echnology transferB次元官网网址 required to produce the vaccine.

In an email Wednesday evening, Novavax said it remains committed to making its vaccine in Canada.

B次元官网网址淣ovavax continues to make progress towards establishing local manufacturing capabilities in partnership with NRC/(Biologics Manufacturing Centre), with manufacturing of process performance qualification batches expected to begin in early 2023,B次元官网网址 the company said.

Laurie Bouchard, a spokeswoman for Champagne, said in an email that B次元官网网址渁t this time, there are no expected changes to the partnership between Novavax and the BMC.B次元官网网址

The company is currently the NRCB次元官网网址檚 only client at the Montreal biomanufacturing centre, which was completed in 2021 and is intended to produce biopharmaceuticals such as vaccines.

B次元官网网址淲eB次元官网网址檙e continuing to explore options with potential collaborators on producing vaccines and other biologics at the facility on its second production line,B次元官网网址 Christine Jodoin, the vice-president of strategic initiatives at the NRC, wrote in an email.

Canada has struggled to ramp up COVID-19 vaccine production. A deal with Chinese company CanSino Biologics B次元官网网址 which could have seen the companyB次元官网网址檚 vaccine manufactured at the Montreal facility B次元官网网址 fell apart in the summer of 2020.

Mitsubishi Chemical announced early last month that another company planning the commercial manufacture of COVID-19 vaccines in Canada, Quebec-based Medicago Inc., would be shut down.

However, in August, vaccine giant Moderna announced it would build a new manufacturing facility in the Montreal suburb of Laval.

Bouchard said the governmentB次元官网网址檚 approach to acquiring COVID-19 vaccines ensured Canadians had access to vaccines quickly and reversed 40 years of decline in CanadaB次元官网网址檚 biomanufacturing sector.

B次元官网网址淪o far, we have invested $1.8 billion towards 33 projects across the country and we continue to invest in the researchers, talent and innovation that will keep strengthening the Canadian life sciences ecosystem,B次元官网网址 she wrote.

B次元官网网址擩acob Serebrin, The Canadian Press





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